Nzira yekubata sei nhumbu nekukurumidza pane metformin? .
Gynecologists vanoshandisa metformin sechikamu chekurapa kubata nhumbu; tinokuudza sei:
Metformin kubata pamuviri
Vakadzi vane insulin kudzivisa angave akasiyana siyana matambudziko echikadzi , kusanganisira kunetsekana kubata pamuviri. Naizvozvo, gynecologists fungisisa metformin kubatsira mukadzi kudzora insulin kusagadzikana uye nokudaro kuchengetedza yakakwana kumwedzi uye kuita nhumbu.
Metformin haina kuita sekurapa kushaya mbereko , asi izvo inobatsira kudzora kumwedzi kwevakadzi vanobatwa ne insulin kudzivisa uye saizvozvo kuwana nhumbu zviri nyore . Zvakare, kana mukadzi achidzora insulin yake kuramba, haangove nepamuviri chete asi achaderedza zvakanyanya njodzi yekurasikirwa nemwana mumwedzi inotevera yekuzvitakura.
Kana mukadzi achinge akwanisa kuenzanisa chinzvimbo chake chehormone, achiratidza Chiremba Mukati José Víctor Manuel Rincón Ponce, weMexico Social Security Institute, kutenderera kwake kwekuenda kumwedzi kunoitwa zvekare, uye nekudaro zvichave nyore kugadzira nharaunda yakakwana yemuviri wake vane uye chengetedza yakazara-temu nhumbu.
Kuwana pamuviri uchitambura ne polycystic ovary syndrome
Polycystic ovary syndrome, chirwere chinoratidzirwa nekusaenzana kwemamosi, shanduko yehomoni, uye kutaridzika kwemazhinji cysts mumazai, zvinokanganisa vangangoita 8% yevakadzi huwandu. Chii chinokonzera chirwere ichi chichiri kusahadzika, uye kuongororwa uye kurapwa kwakakurukurwa zvakanyanya.
Chinozivikanwa ndechekuti ichi ndicho chimwe chezvikonzero zvikuru zvekushaya mbereko muvakadzi, uko kwaunogona kuwedzera kumwe kusagadzikana kwemetabolism, sekufutisa kana kusagadzikana kwe insulin.
Chidzidzo chakaitwa neboka revatsvakurudzi vanobva kumayunivhesiti akasiyana eAmerica, kuitira kuti vabvumidze mhedzisiro yezvidzidzo zvidiki pa nzira yakanakisa yekurapa kushaya mbereko muvakadzi vane polycystic ovarian syndrome , uye iyo yakaburitswa muThe New magazine England Journal of Medicine, inotsanangura kuti mushonga wekare waishandiswa kukurudzira ovulation kuburikidza nekuita kwayo pane follicle-inomutsa mahormone, clomiphene citrate, ndiyo yakanyanya kunaka sarudzo kune vakadzi vanotambura nechirwere ichi kuti vave nepamuviri , ndiyo zvakare iri nyore kurapwa, yakachipa, isina njodzi uye inoshanda.
Yekushandisa kwazvino uno yaive metformin, mushonga unoshandiswa kurapa rudzi rwechipiri chirwere cheshuga, icho nekuvandudza glucose uye kufutisa kunoda kubata pamuviri. Chidzidzo ichi chakaitwa pamwe nevakadzi mazana matanhatu mazana matanhatu vasina mbereko nekuda kwechirwere ichi uye chakavagovanisa mumapoka matatu, rimwe boka rakagashira antidiabetic drug (yakawedzera-kuburitsa metformin), imwe iyo ovulation inducer (clomiphene citrate) uye wechitatu akagamuchira mubatanidzwa wemaviri mishonga . Iyo yekurapa uye yekutevera yakatora inokwana kwemasvondo makumi matatu kana kusvika vawana nhumbu.
Pakupera kwekudzidza, vakadzi avo vakanga vagamuchira clomiphene vakaratidza mwero wekuzvarwa katatu zvakapfuura iwo weboka re metformin; pamusoro pezvo, iyo yekutanga yaivewo nenhamba yepamusoro yenhumbu dzakawanda.
Vaya vakatora mubatanidzwa wemishonga iyi miviri vakaratidza huwandu hwekuvhara mazai hwakakwira kupfuura hwese, asi kuzvarwa hakuna kuzadzikiswa, kunyangwe hazvo vakaenzana nhumbu dzakawanda neboka rakagashira iyo ovulation inducer.
Zvidzidzo zvakapfuura zvainge zvaratidza kupesana neizvi, asi mhedzisiro haina kuongororwa pakuzvarwa, asi muhuwandu hweovulation, inova chishuwo chevakadzi vanotambura nedambudziko iri.
Zvinyorwa:
Zvinyorwa Tarisa Mamwe mashoko
- Barbieri RL, et al. (2017). Metformin yekurapa iyo polycystic ovary syndrome.
uptodate.com/contents/metformin-for-treatment-of-the-polycystic-ovary-syndrome - Zvipire kusarudzo dzakanaka kubatsira kudzivirira kuremara kwekuzvarwa. (2017).
cdc.gov/ncbddd/birthdefects/prevention.html - Kunzwisisa DS, et al. (2011). Metformin kurapwa panguva yekuzvitakura. DOI:
doi.org/10.2337/dc11-1153 - Mahwendefa eglucophage (metformin hydrochloride); Glucophage XR (metformin hydrochloride) akawedzera-kuburitsa mapiritsi. (2017).
accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf - Vashandi veMayo Clinic. (2017). Gestational chirwere cheshuga.
mayoclinic.org/diseases-conditions/gestational-diabetes/basics/risk-factors/con-20014854
Zviri Mukati